If a client experiences a headache after an increased dose of isosorbide dinitrate (Imdur), what should the nurse do?

The correct response is to administer the increased dose along with acetaminophen. Isosorbide dinitrate is a nitrate used for angina, and headaches are a common side effect, especially when the dosage is increased. This occurs because nitrates can cause vasodilation, leading to increased blood flow to the brain, which can trigger a headache.

When managing this situation, it's appropriate to continue with the prescribed treatment, as the headache is a recognized side effect rather than an indication to stop therapy. Administering acetaminophen can help alleviate the headache without interfering with the effectiveness of the isosorbide dinitrate. This combination allows the client to continue receiving their treatment while addressing an immediate discomfort caused by side effects.

Other options, such as holding the dose or contacting the healthcare provider, are less appropriate in this context because the headache is not necessarily a contraindication for continuing the increased dose. Adjusting the regimen or contacting a provider might be unnecessary at this stage unless the headache becomes severe or persistent, which is not indicated here.